The extremely unique phase characteristics of Shim-pack GIST Phenyl are critical to resolving compounds that could not be separated with a C18 or C8 phase column. In addition to π-π interactions, Shim-pack GIS Phenyl provides hydrogen bonding secondary interactions, which results in retaining polar compounds at the same time. As the phenyl groups are directly bonded to the silica gel, Shim-pack GIS Phenyl is also capable of the analysis of structural isomers due to its high stereo-selectivity.